Fumidil-B Oral Powder Fumagillin, 500g

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The only registered treatment for nosema. Feed in sugar syrup during the spring and fall to keep your spore counts low. No residue in honey when used as directed. Cost effective. Reduces expensive colony replacement and results in more productive colonies. Add one 500 gram bottle to 1 gallon of water to dissolve. Makes 110 gallons of treatment when added to 110 gallons of syrup.


Prevention and treatment of Nosema apis

Dosage and Administration

Spring Treatment

  • Administer a medicated syrup as below and administer 8 times with an interval of a week.

Mix 25g of Fumidil-B per medicated syrup as below and administer 8 times with an interval of a week.

Colonies Medicated syrup Dosage
Over 8 colonies 25L 1L
4 to 7 colonies 18L 0.75L
3 colonies 12L 0.5L


1) Put into the water supply. (All of the bees can be treated at the same time)

2) Spray the package and the inner walls of the bee hive. (for severe infections)

Autumn Treatment

  • The autumn treatment must be done the same way than the spring treatment.

Note: If you are ordering medication in advance, please contact us to determine the expiration date of our current inventory.

Disclaimer: Results may very


  • 2.80 x 3.20 x 6.80 inches
  • 1.30 LBS
  • Only registered F.D.A. registered treatment for nosema
  • Treat colony in the Spring to increase honey yields and kill nosema
  • Active Ingredient: Fumagillin bicyclohexylammonium
  • Animal use only
  • Prevention and treatment of Nosema apis
  • Store in cool and dark place under 25 Celsius
  • Do not use immediately before or during honey flow
  • Keep out of reach of children and animals
  • This product can only be shipped within the United States.

Nosema is a fungal disease commonly found in honey bees. Honey bees unknowingly consume nosema causing spores whether from contaminated honeycomb or by interactions with other bees. Once the bee has consumed these spores, they begin to germinate in the bee’s mid-gut. Eventually, this leaves the bee with nutrient loss and cell damage. The weakened bee is then more susceptible to disease and is also less productive. One nosema spore can multiply into several million spores within one worker bee. These spores pass through the honey bee’s system which can further contaminate the hive and neighboring colonies.